Category Archives: Cell Therapy

Endocytosis in deciding fate of Embryonic Stem Cells

Posted on January 12, 2016

Scientists at NCCS are investigating the role of endocytosis and vesicular transport in deciding the future state of an undifferentiated embryonic stem cell. Using experimental techniques like large scale siRNA screening, reprogramming assays and biophysical manipulation of mouse embryos, they are studying how modifications to cellular or vesicular transport determines whether an embryonic stem cell maintains pluripotency or differentiates into a specific cell type. Continue reading →

Posted in Biopharma, Cell Biology, Cell Therapy, Stem Cells

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Tapping into Pluripotent Differentiation Potentials of Embryonic Stem Cells

Posted on January 9, 2016

Using the pluripotent embryonic stem cells as a model system, scientists at NCCS are investigating the epigenetic factors and molecular determinants which are involved in deciding and controlling differentiation of stem cells into specific cellular lineages. Continue reading →

Posted in Biopharma, Cell Therapy, Genetics, In-vitro Platform, Regenerative medicine, Stem Cells

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An Elegant Model for Studying Early Embryonic Development

Posted on January 9, 2016

Scientists at NCCS are studying the early embryonic development using embryonic stem cells derived from the blastula stage embryo. These embryonic stem cells possess unique characteristics of indefinite self renewal and pluripotency; and are capable of precisely recapitulating the early embryogenic development, thereby serving as an elegant model for studying the developmental events occurring during embryogenesis. Continue reading →

Posted in Biopharma, Cell Therapy, Genetics, In-vitro Platform, Stem Cells

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Dendritic Cells for Cancer Immunotherapy

Posted on October 27, 2015

Scientists at NCCS have developed a novel two-step method for large-scale generation of mature, functional Dendritic Cells (DC) from Umbilical cord blood (UCB). This technology will aid in development of dendritic cell based vaccines for cancer immunotherapy. Continue reading →

Posted in Biopharma, Cell Therapy, Stem Cells

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In-vitro Bone Marrow Niche Platform and Pre-clinical Screening Kit

Posted on October 3, 2015

An artificial bone marrow microenvironment (ABME) platform for enhancing and regulating in-vitro as well as in vivo formation of stem cells has been created by scientist at NCCS, Pune. This technology can be incorporated into high throughput and micro-fluidic devices for drug screening and in-vitro toxicology testing. Continue reading →

Posted in Biopharma, Cell Therapy, In-vitro Platform, Regenerative medicine, Stem Cells, Umbilical Cord Blood Banking

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An Overview of NCCS Capabilities

Posted on September 19, 2015
Capability Area NCCS Scientists/ Consultants
Cancer Biology Dr. Sharmila Bapat, Dr. Padma Shastry, Dr. Anjali Shiras, Dr. Mohan Wani, Dr. Gopal Kundu, Dr. Samit Chattopadhyay, Dr. Manoj Kumar Bhat, Dr. Sandhya Sitaswad, Dr. Girdhari Lal, Dr. Srikanth Rapole, Dr. Manas Santra
Cell Biology Dr. Shekhar Mande, Dr. Mohan Wani, Dr. Debashis Mitra, Dr. Prakash Deshpande, Dr. Jomon Joseph,  Dr. Bhaskar Saha, Dr. Milind Patole, Dr. Arvind Sahu, Dr. M. V. Krishnasastry, Dr. Vasudevan Seshadri, Dr. Radha Chauhan, Dr. Janesh Kumar, Dr. Girdhari Lal, Dr. Shailza Singh, Dr. Deepa Subramanyam
Genetics Dr. Sharmila Bapat, Dr. Anjali Shiras, Dr. Samit Chattopadhyay, Dr. Jomon Joseph, Dr. Vasudevan Seshadri, Dr. Manas Santra, Dr. Vidisha Tripathi
Immunology  Dr. Mohan Wani, Dr. Bhaskar Saha, Dr. Arvind Sahu, Dr. Girdhari Lal, Dr. Shailza Singh
Metabolic Diseases Dr. Manoj Kumar Bhat, Dr. Sandhya Sitaswad
Microbial Biology Dr. Milind Patole, Dr. Yogesh Shouche, Dr. Shailza Singh
Neuroscience Dr. Amitabha Majumdar, Dr. Janesh Kumar
Stem Cells Dr. Vaijayanti Kale, Dr. Lalita Limaye, Dr. Anjali Shiras, Dr. Nibedita Lenka, Dr. Deepa Subramanyam

Posted in Biopharma, Cancer Biology, Cell Biology, Cell Therapy, Diagnostics, Genetics, Immunology, In-vitro Platform, Medical Device, Metabolic Diseases, Microbial Biology, Neuroscience, Nutraceutical, Regenerative medicine, Stem Cells, Umbilical Cord Blood Banking

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