Scientists at NCCS have developed an in-vitro anti-diabetic drug screening system based on glucose transporter 4 (GLUT4) activity in a novel cell line (CHO-HIRc-mycGLUT4eGFP). Using this system, GLUT4 translocation under stimulation can be visualized by live cell imaging and captured real-time for qualitative and quantitative analysis of GLUT4 on the cell membrane. Continue reading
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