Category Archives: Microbial Biology

Immune Modulation using Synthetic Signaling Circuit

Efficient immune signalling response against pathogens is crucial for resolving infections. However, many pathogens thrive by evolving strategies to evade the host immune response. Scientists at NCCS are exploring ways to rewire immune signaling pathways or networks by using synthetic signaling circuits. Continue reading

Synthetic Biology Approach for Resolving Diseases

Scientists at NCCS are tapping into synthetic biology techniques for understanding the dynamics of infectious diseases like Leishmaniasis and designing simple to complex synthetic circuits made of biological building blocks (bio bricks), which can be used to reprogram various pathways inside a variety of cells involved in the pathogenesis. Continue reading

Structure Function Analysis of Proteins in M. tuberculosis

Exploiting the state-of-art technology for increasing the knowledge base on micro organisms, scientists at NCCS are studying the structure and functional correlation of proteins derived from Mycobacterium tuberculosis. Using crystallography and in-silico methods, they are analyzing the heat shock responses mediated by proteins such as GroEL chaperonin, oxidative stress induced redox reactions and enzymatic reaction mediated electron transport mechanisms in the cell. Continue reading

An Overview of NCCS Capabilities

Capability Area NCCS Scientists/ Consultants
Cancer Biology Dr. Sharmila Bapat, Dr. Padma Shastry, Dr. Anjali Shiras, Dr. Mohan Wani, Dr. Gopal Kundu, Dr. Samit Chattopadhyay, Dr. Manoj Kumar Bhat, Dr. Sandhya Sitaswad, Dr. Girdhari Lal, Dr. Srikanth Rapole, Dr. Manas Santra
Cell Biology Dr. Shekhar Mande, Dr. Mohan Wani, Dr. Debashis Mitra, Dr. Prakash Deshpande, Dr. Jomon Joseph,  Dr. Bhaskar Saha, Dr. Milind Patole, Dr. Arvind Sahu, Dr. M. V. Krishnasastry, Dr. Vasudevan Seshadri, Dr. Radha Chauhan, Dr. Janesh Kumar, Dr. Girdhari Lal, Dr. Shailza Singh, Dr. Deepa Subramanyam
Genetics Dr. Sharmila Bapat, Dr. Anjali Shiras, Dr. Samit Chattopadhyay, Dr. Jomon Joseph, Dr. Vasudevan Seshadri, Dr. Manas Santra, Dr. Vidisha Tripathi
Immunology  Dr. Mohan Wani, Dr. Bhaskar Saha, Dr. Arvind Sahu, Dr. Girdhari Lal, Dr. Shailza Singh
Metabolic Diseases Dr. Manoj Kumar Bhat, Dr. Sandhya Sitaswad
Microbial Biology Dr. Milind Patole, Dr. Yogesh Shouche, Dr. Shailza Singh
Neuroscience Dr. Amitabha Majumdar, Dr. Janesh Kumar
Stem Cells Dr. Vaijayanti Kale, Dr. Lalita Limaye, Dr. Anjali Shiras, Dr. Nibedita Lenka, Dr. Deepa Subramanyam